How would you investigate a new palpable breast lump after a recent negative screening mammogram?

Instruction: Choose the next assessment for this patient and explain how you would handle disagreement between the examination and imaging.

Context: A 48-year-old has noticed a new persistent breast lump for three weeks. The referring clinician describes a firm focal mass, and the patient can indicate its exact location. Screening mammography six months earlier was reported negative. There has been no diagnostic evaluation of the new symptom.

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I would arrange a prompt diagnostic breast assessment rather than send the patient back to routine screening. I would obtain the relevant history, review the prior images, and arrange targeted ultrasound of the precise palpable site...

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